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Adaptive enrichment designs for confirmatory trials

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Publication:6625662
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DOI10.1002/sim.7946zbMATH Open1545.62396MaRDI QIDQ6625662

Philip W. Lavori, Tze Leung Lai, Ka Wai Tsang

Publication date: 28 October 2024

Published in: Statistics in Medicine (Search for Journal in Brave)




zbMATH Keywords

heterogeneityadaptive designsclinical trials


Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)


Cites Work

  • Asymptotically efficient adaptive allocation rules
  • Adaptive treatment allocation and the multi-armed bandit problem
  • Sequential experimentation in clinical trials. Design and analysis
  • Power, sample size and adaptation considerations in the design of group sequential clinical trials
  • Efficient Adaptive Randomization and Stopping Rules in Multi-arm Clinical Trials for Testing a New Treatment
  • Adaptive and nonadaptive group sequential tests


Related Items (3)

Subgroup analysis and adaptive experiments crave for debiasing ⋮ Finding the best subgroup with differential treatment effect with multiple outcomes ⋮ Adaptive trial designs in diagnostic accuracy research






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