Testing and correcting for weak and pleiotropic instruments in two-sample multivariable Mendelian randomization

DOI10.1002/sim.9133zbMath1546.62647MaRDI QIDQ6628230

Wes Spiller, Eleanor Sanderson, Jack Bowden

Publication date: 29 October 2024

Published in: Statistics in Medicine (Search for Journal in Brave)

zbMATH Keywords

instrument validityCochran's \(Q\)-statistictwo-sample Mendelian randomizationinstrument strengthmultivariable Mendelian randomization

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

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