Optimal adaptive promising zone designs

DOI10.1002/sim.9339zbMATH Open1547.62373MaRDI QIDQ6628338

Lingyun Liu, Apurva Bhingare, Pralay Senchaudhuri, Cyrus R. Mehta

Publication date: 29 October 2024

Published in: Statistics in Medicine (Search for Journal in Brave)

zbMATH Keywords

interim analysisgroup sequentialBayesian adaptive designsample size re-estimationtrial optimizationmid-course correctionsmallest clinically meaningful effecttrial modification

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites Work

• Unnamed Item
• Adaptive Group Sequential Designs for Clinical Trials: Combining the Advantages of Adaptive and of Classical Group Sequential Approaches
• Discrete Sequential Boundaries for Clinical Trials
• Optimal Conditional Error Functions for the Control of Conditional Power
• Designed Extension of Studies Based on Conditional Power
• On the inefficiency of the adaptive design for monitoring clinical trials
• Modification of Sample Size in Group Sequential Clinical Trials
• Optimal promising zone designs
• A variational approach to optimal two-stage designs
• Optimal planning of adaptive two-stage designs

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