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Extending the continual reassessment method to accommodate step-up dosing in phase I trials - MaRDI portal

Extending the continual reassessment method to accommodate step-up dosing in phase I trials

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Publication:6628516

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DOI10.1002/sim.9487zbMath1547.62153MaRDI QIDQ6628516

Thomas M. Braun, Francois Mercier

Publication date: 29 October 2024

Published in: Statistics in Medicine (Search for Journal in Brave)

zbMATH Keywords

conditional probability Bayesian inference dose escalation adaptive clinical trial fractionated dosing up-titration

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

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