Dose finding studies for therapies with late-onset toxicities: a comparison study of designs

DOI10.1002/SIM.9593zbMATH Open1547.62135MaRDI QIDQ6629421

Author name not available (Why is that?), Oliver Boix, Dimitris Kontos, Thomas Jaki

Publication date: 30 October 2024

Published in: Statistics in Medicine (Search for Journal in Brave)

zbMATH Keywords

dose-findingphase I trialsmodel-basedmodel-assistedlate-onset toxicities

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites Work

• Design and Analysis of Phase I Clinical Trials
• Determining the Effective Sample Size of a Parametric Prior
• Bayesian decision procedures based on logistic regression models for dose-finding studies
• Sequential Designs for Phase I Clinical Trials with Late‐Onset Toxicities
• Quantification of prior impact in terms of effective current sample size
• Predictively consistent prior effective sample sizes
• Non-parametric optimal design in dose finding studies

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