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BLAST: Bayesian latent subgroup design for basket trials accounting for patient heterogeneity

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Publication:6641422
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DOI10.1111/rssc.12255MaRDI QIDQ6641422

Yiyi Chu, Ying Yuan

Publication date: 20 November 2024

Published in: Journal of the Royal Statistical Society. Series C. Applied Statistics (Search for Journal in Brave)




zbMATH Keywords

subgroupstargeted therapyprecision medicinelongitudinal biomarkerBayesian adaptive designbasket trials


Mathematics Subject Classification ID

Applications of statistics (62Pxx)



Related Items (6)

Constrained hierarchical Bayesian model for latent subgroups in basket trials with two classifiers ⋮ A generalized calibrated Bayesian hierarchical modeling approach to basket trials with multiple endpoints ⋮ ComPAS: a Bayesian drug combination platform trial design with adaptive shrinkage ⋮ Hierarchical Bayesian clustering design of multiple biomarker subgroups (HCOMBS) ⋮ Bayesian local exchangeability design for phase II basket trials ⋮ Bayesian methods for the analysis of early-phase oncology basket trials with information borrowing across cancer types






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