The influence of T cell development on pathogen specificity and autoreactivity

DOI10.1007/S10955-011-0403-8zbMath1259.82144arXiv1108.0530OpenAlexW3098730330WikidataQ59062745 ScholiaQ59062745MaRDI QIDQ691023

Andrej Košmrlj, Arup K. Chakraborty, Mehran Kardar

Publication date: 29 November 2012

Published in: Journal of Statistical Physics (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1108.0530

zbMATH Keywords

statistical mechanicsautoimmune T cellsT cell pathogen specificitythymic selection

Mathematics Subject Classification ID

Statistical mechanics of polymers (82D60) Cell biology (92C37)

Related Items (1)

Broad cross-reactivity of the T-cell repertoire achieves specific and sufficiently rapid target searching

Cites Work

• Explaining high alloreactivity as a quantitative consequence of affinity-driven thymocyte selection

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