Multi-objective optimal designs in comparative clinical trials with covariates: the reinforced doubly adaptive biased coin design

DOI10.1214/12-AOS1007zbMath1257.62082arXiv1206.0576OpenAlexW3102828080MaRDI QIDQ693725

Alessandro Baldi Antognini, Maroussa Zagoraiou

Publication date: 10 December 2012

Published in: The Annals of Statistics (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1206.0576

zbMATH Keywords

ethicsinformation criteriabalanceCARA designs

Mathematics Subject Classification ID

Asymptotic properties of nonparametric inference (62G20) Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05) Sequential statistical design (62L05)

Related Items (5)

Response-adaptive randomization in clinical trials: from myths to practical considerations ⋮ Nonparametric covariate-adjusted response-adaptive design based on a functional urn model ⋮ Multi-objective optimal designs in comparative clinical trials with covariates: the reinforced doubly adaptive biased coin design ⋮ Corrigendum to: ``On recent advances in optimal allocation designs in clinical trials ⋮ On the almost sure convergence of adaptive allocation procedures

Cites Work

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• Optimal Adaptive Designs for Binary Response Trials
• Multi-objective optimal designs in comparative clinical trials with covariates: the reinforced doubly adaptive biased coin design
• Efficient randomized-adaptive designs
• A new family of covariate-adjusted response adaptive designs and their properties
• Handling covariates in the design of clinical trials
• Asymptotic properties of doubly adaptive biased coin designs for multitreatment clinical trials.
• Asymptotic properties of covariate-adjusted response-adaptive designs
• An adaptive randomized design with application to estimation
• Adaptive designs for normal responses with prognostic factors
• Compound optimal allocation for individual and collective ethics in binary clinical trials
• The covariate-adaptive biased coin design for balancing clinical trials in the presence of prognostic factors
• A theory for testing hypotheses under covariate-adaptive randomization
• Optimum biased coin designs for sequential clinical trials with prognostic factors
• On the Equivalence of Constrained and Compound Optimal Designs
• The Equivalence of Constrained and Weighted Designs in Multiple Objective Design Problems
• The Comparison of Designs for Sequential Clinical Trials with Covariate Information
• Implementing Optimal Allocation in Sequential Binary Response Experiments
• The Theory of Response‐Adaptive Randomization in Clinical Trials

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