Optimal control for resistance and suboptimal response in CML

DOI10.1016/J.MBS.2010.06.005zbMath1197.92024OpenAlexW2066848036WikidataQ37773634 ScholiaQ37773634MaRDI QIDQ709161

Chahrazed Benosman, Bedr'Erddine Ainseba

Publication date: 15 October 2010

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.mbs.2010.06.005

zbMATH Keywords

control problemshematopoiesischronic myeloid leukemiaoptimization and variational techniquesimatinib therapysuboptimal response and resistance

Mathematics Subject Classification ID

Applications of optimal control and differential games (49N90) Dynamical systems in biology (37N25) Medical applications (general) (92C50) Existence theories for optimal control problems involving ordinary differential equations (49J15) Dynamical systems in control (37N35)

Related Items (12)

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Cites Work

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• Numerical integration of a mathematical model of hematopoietic stem cell dynamics
• Optimal HIV treatment by maximising immune response
• A mathematical model of hematopoiesis. I: Periodic chronic myelogenous leukemia
• Optimal control of treatment in a mathematical model of chronic myelogenous leukemia

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