Optimal designs for response functions with a downturn

DOI10.1016/J.JSPI.2010.07.003zbMath1197.62105OpenAlexW2004991076MaRDI QIDQ710822

Min Yang, Nancy Flournoy, Seung Won Hyun

Publication date: 22 October 2010

Published in: Journal of Statistical Planning and Inference (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jspi.2010.07.003

zbMATH Keywords

D-optimalityA-optimalityexperimental designdose-response\(EC_{50}\)D\(_A\)-optimalityendocrine-disrupting chemicalslaboratory studiesnonlinear response functionoptimal weightspeak dosesuccessive mean differencestoxicological assays

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05) Medical applications (general) (92C50)

Related Items (2)

A procedure for finding an improved upper bound on the number of optimal design points ⋮ Optimal designs based on the maximum quasi-likelihood estimator

Cites Work

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• Support points of locally optimal designs for nonlinear models with two parameters
• A note on optimal designs for two or more treatment groups
• Adaptive designs for selecting drug combinations based on efficacy-toxicity response

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