The flatness of lamellipodia explained by the interaction between actin dynamics and membrane deformation

DOI10.1016/J.JTBI.2015.05.010zbMath1343.92054OpenAlexW1897669845WikidataQ47649266 ScholiaQ47649266MaRDI QIDQ739203

Christoph Winkler, Christian Schmeiser

Publication date: 18 August 2016

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2015.05.010

zbMATH Keywords

finite elementactin filamentlamellipodium

Mathematics Subject Classification ID

Biomechanics (92C10) Cell movement (chemotaxis, etc.) (92C17)

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Uses Software

• Actin Segmentation

Cites Work

• Simulation of lamellipodial fragments
• An extended filament based lamellipodium model produces various moving cell shapes in the presence of chemotactic signals
• Finite element modeling of lipid bilayer membranes
• Models for actin polymerization motors

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