The search for a DNA target in the nucleus

DOI10.1016/j.physleta.2009.11.027zbMath1235.92022OpenAlexW2154100371WikidataQ58052124 ScholiaQ58052124MaRDI QIDQ763851

G. Malherbe, David Holcman

Publication date: 2 April 2012

Published in: Physics Letters. A (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.physleta.2009.11.027

Mathematics Subject Classification ID

Biochemistry, molecular biology (92C40) Cell biology (92C37) Applications of Brownian motions and diffusion theory (population genetics, absorption problems, etc.) (60J70)

Related Items (4)

Polymer physics of nuclear organization and function ⋮ Extreme narrow escape: shortest paths for the first particles among \(n\) to reach a target window ⋮ Stochastic modeling of gene activation and applications to cell regulation ⋮ The influence of spatial variation in chromatin density determined by X-ray tomograms on the time to find DNA binding sites

Cites Work

• Reaction rate of small diffusing molecules on a cylindrical membrane
• A Guide to First-Passage Processes
• Strong Localized Perturbations of Eigenvalue Problems
• Summing Logarithmic Expansions for Singularly Perturbed Eigenvalue Problems
• Diffusion on a Sphere with Localized Traps: Mean First Passage Time, Eigenvalue Asymptotics, and Fekete Points
• Diffusion escape through a cluster of small absorbing windows
• Optimizing the fundamental Neumann eigenvalue for the Laplacian in a domain with small traps
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