Analysis of iron kinetics: Identifiability, experiment design, and deterministic interpretations of a stochastic model

DOI10.1016/0025-5564(84)90072-5zbMath0552.92009OpenAlexW2088089367MaRDI QIDQ801844

Michael H. Nathanson, Gordon D. McLaren, Gerald M. Saidel

Publication date: 1984

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/0025-5564(84)90072-5

zbMATH Keywords

D-optimal designblood- sampling procedureextraplasma sojourn timesferrokineticslinear, time invariant 4-compartment modelsplasma clearance rateradioiron tracer kineticsred- cell concentrationstochastic reflux model

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Optimal statistical designs (62K05) System identification (93B30) Inverse problems involving ordinary differential equations (34A55) Physiological, cellular and medical topics (92Cxx)

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Qualitative and quantitative experiment design for phenomenological models - a survey

Cites Work

• Compartment analysis: An inverse problem
• Identifiability of linear and nonlinear dynamical systems
• Expressing the normal distribution with covariance matrix A + B in terms of one with covariance matrix A
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