The application of a multistage model that incorporates DNA damage and repair to the analysis of initiation/promotion experiments

DOI10.1016/0025-5564(91)90079-XzbMath0732.92005WikidataQ38515041 ScholiaQ38515041MaRDI QIDQ809919

F. Rippmann, Christopher J. Portier, Annette Kopp-Schneider

Publication date: 1991

Published in: Mathematical Biosciences (Search for Journal in Brave)

zbMATH Keywords

DNA damageDNA repaircell replicationmultistage model of carcinogenesisnumber of detectable clones of initiated cellstwo-stage skin-painting experiment

Mathematics Subject Classification ID

Medical applications (general) (92C50) Biochemistry, molecular biology (92C40)

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Cites Work

• The application of a multistage model that incorporates DNA damage and repair to the analysis of initiation/promotion experiments
• Two-event models for carcinogenesis: Incidence curves for childhood and adult tumors
• A pseudo-steady state approximation for stochastic chemical kinetics
• Regression Analysis of Poisson-Distributed Data
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