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Phantom bursting may underlie electrical bursting in single pancreatic \(\beta\)-cells

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Publication:827876
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DOI10.1016/J.JTBI.2020.110346zbMath1455.92037OpenAlexW3033017505WikidataQ96160386 ScholiaQ96160386MaRDI QIDQ827876

Theodore Vo, Richard Bertram, Mehran Fazli

Publication date: 13 January 2021

Published in: Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.jtbi.2020.110346


zbMATH Keywords

oscillationselectrical activityfast-slow analysisglycolytic oscillationsislet


Mathematics Subject Classification ID

Cell biology (92C37)





Cites Work

  • A calcium-based phantom bursting model for pancreatic islets
  • Fast-slow analysis of the integrated oscillator model for pancreatic \(\beta\)-cells
  • Transitions between bursting modes in the integrated oscillator model for pancreatic \(\beta\)-cells
  • Phantom bursting is highly sensitive to noise and unlikely to account for slow bursting in \(\beta\)-cells: considerations in favor of metabolically driven oscillations
  • Multi-timescale systems and fast-slow analysis
  • Slow variable dominance and phase resetting in phantom bursting




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