Compromise design for combination experiment of two drugs

DOI10.1016/j.csda.2020.107150OpenAlexW3107571655MaRDI QIDQ830471

Hengzhen Huang, Xue-Ping Chen

Publication date: 7 May 2021

Published in: Computational Statistics and Data Analysis (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.csda.2020.107150

zbMATH Keywords

design of experimentsadditivityuniform designsynergismresponse surface model

Mathematics Subject Classification ID

Statistics (62-XX)

Related Items (2)

Robust designs for dose-response studies: model and labelling robustness ⋮ Optimal designs for semi-parametric dose-response models under random contamination

Uses Software

• fields
• DiceDesign

Cites Work

• Uniform distributions in a class of convex polyhedrons with applications to drug combination studies
• Designs for approximately linear regression: Two optimality properties of uniform designs
• Experimental designs for drug combination studies
• Optimal experimental designs for estimating the drug combination index in toxicology
• Optimal designs for dose-response models with linear effects of covariates
• Theory and application of uniform experimental designs
• A generalized discrepancy and quadrature error bound
• Mathematical Statistics
• A Generalized Response Surface Model with Varying Relative Potency for Assessing Drug Interaction
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