Maximum likelihood and Bayesian methods for estimating the distribution of selective effects among classes of mutations using DNA polymorphism data

DOI10.1016/S0040-5809(02)00050-3zbMath1104.62118WikidataQ33186242 ScholiaQ33186242MaRDI QIDQ849468

Rasmus Nielsen, Daniel L. Hartl, Carlos D. Bustamante

Publication date: 31 October 2006

Published in: Theoretical Population Biology (Search for Journal in Brave)

zbMATH Keywords

EM algorithmpopulation geneticsBayesian statisticsGibbs samplingMCMChierarchical modelsPoisson random fieldSNPs

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Bayesian inference (62F15) Problems related to evolution (92D15) Numerical analysis or methods applied to Markov chains (65C40) Protein sequences, DNA sequences (92D20)

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Uses Software

• BayesDA

Cites Work

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• On the number of segregating sites in genetical models without recombination
• Ancestral processes with selection
• Simulation of selected genealogies.
• Most recent common ancestor probability distributions in gene genealogies under selection.
• The sampling theory of selectively neutral alleles
• Equation of State Calculations by Fast Computing Machines
• Monte Carlo sampling methods using Markov chains and their applications
• Simulation of `hitch-hiking' genealogies