Asymptotics and bioavailability in a 17-compartment pharmacokinetic model with enterohepatic circulation and remetabolization

DOI10.1016/J.MBS.2006.02.001zbMath1099.92028OpenAlexW2004278658WikidataQ51943691 ScholiaQ51943691MaRDI QIDQ850104

Pavol Zlatoš, Stefan Horkovics-Kovats

Publication date: 15 November 2006

Published in: Mathematical Biosciences (Search for Journal in Brave)

Full work available at URL: https://doi.org/10.1016/j.mbs.2006.02.001

zbMATH Keywords

identifiabilitybioavailabilityenterohepatic circulationefficiency of enterohepatic circulationremetabolizationtransition and elimination probabilities

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Control/observation systems governed by functional relations other than differential equations (such as hybrid and switching systems) (93C30)

Cites Work

• On the structural identifiability of biological compartmental systems in a general input-output configuration
• Asymptotics and bioavailability in multicompartment pharmacokinetic models with enterohepatic circulation

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