The role of family-based designs in genome-wide association studies

DOI10.1214/08-STS280zbMath1329.62430arXiv1010.4629MaRDI QIDQ908106

Nan M. Laird, Christoph Lange

Publication date: 3 February 2016

Published in: Statistical Science (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1010.4629

zbMATH Keywords

genetic associationTDTFBATtwo-stage designsPBAT

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10)

Related Items (2)

Causal inference in genetic trio studies ⋮ Methodological issues in multistage genome-wide association studies

Uses Software

• PBAT
• STRUCTURE
• UNPHASED
• SimWalk2

Cites Work

• Genome-wide significance levels and weighted hypothesis testing
• Genomic Control for Association Studies
• A multivariate family-based association test using generalized estimating equations: FBAT-GEE
• Genetics, Alzheimer’s Disease, and Long-Term Care Insurance

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