Robust tests in genome-wide scans under incomplete linkage disequilibrium

DOI10.1214/09-STS314zbMath1329.62440arXiv1010.5091MaRDI QIDQ908129

Gang Zheng, Dmitri Zaykin, Nancy L. Geller, Jungnam Joo, Wu, Colin O.

Publication date: 3 February 2016

Published in: Statistical Science (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1010.5091

zbMATH Keywords

linkage disequilibriumranking and selectiongenome-wide association studiesgenetic modelsefficiency robustnessincomplete LD model

Mathematics Subject Classification ID

Nonparametric hypothesis testing (62G10) Nonparametric robustness (62G35) Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10)

Related Items (7)

Combining dependent F-tests for robust association of quantitative traits under genetic model uncertainty ⋮ Some Statistical Properties of Efficiency Robust Tests with Applications to Genetic Association Studies ⋮ Hybrid Bayes factors for genome-wide association studies when a robust test is used ⋮ A proportional score test over the nuisance parameter space: properties and applications ⋮ Statistical analysis in genetic studies of mental illnesses ⋮ Bayes factor based on a maximum statistic for case-control genetic association studies ⋮ A likelihood ratio test for goodness-of-fit of recessive and dominant models for case-control studies

Uses Software

• Rassoc

Cites Work

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