Ribosome kinetics and aa-tRNA competition determine rate and fidelity of peptide synthesis

DOI10.1016/j.compbiolchem.2007.07.003zbMath1141.92312OpenAlexW2047483227WikidataQ37307443 ScholiaQ37307443MaRDI QIDQ935989

Elsje Pienaar, Hendrik J. Viljoen, Aaron M. Fluitt

Publication date: 12 August 2008

Published in: Computational Biology and Chemistry (Search for Journal in Brave)

Full work available at URL: https://digitalcommons.unl.edu/cgi/viewcontent.cgi?article=1008&context=cbmeviljoen

Mathematics Subject Classification ID

Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45) Biochemistry, molecular biology (92C40)

Related Items (7)

A generalized Michaelis-Menten equation in protein synthesis: effects of mis-charged cognate tRNA and mis-reading of codon ⋮ Performance limits and trade-offs in entropy-driven biochemical computers ⋮ Formulation of the protein synthesis rate with sequence information ⋮ Extrinsic noise effects on ribosomal traffic during the translation process ⋮ Community control in cellular protein production: consequences for amino acid starvation ⋮ Impact of polydispersity and confinement on diffusion in hydrodynamically interacting colloidal suspensions ⋮ The tri-frame model

Cites Work

• A mathematical model for elongation of a peptide chain
• A model of protein translation including codon bias, nonsense errors, and ribosome recycling

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