Sequential monitoring of response-adaptive randomized clinical trials

DOI10.1214/10-AOS796zbMath1194.62095arXiv1010.3901MaRDI QIDQ988004

Hongjian Zhu, Fei-fang Hu

Publication date: 24 August 2010

Published in: The Annals of Statistics (Search for Journal in Brave)

Full work available at URL: https://arxiv.org/abs/1010.3901

zbMATH Keywords

asymptotic propertiessample sizepowertype I errorBrownian processresponse-adaptive randomization

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Central limit and other weak theorems (60F05) Medical applications (general) (92C50) Sequential statistical design (62L05) Sequential statistical analysis (62L10)

Related Items (12)

Group-sequential response-adaptive designs for multi-armed trials ⋮ Bayesian adaptive randomization with compound utility functions ⋮ Asymptotic properties of the sequential empirical ROC, PPV and NPV curves under case-control sampling ⋮ An optimal allocation for response-adaptive designs ⋮ Bayesian doubly adaptive randomization in clinical trials ⋮ Inference in Targeted Group‐Sequential Covariate‐Adjusted Randomized Clinical Trials ⋮ Implementing optimal allocation in clinical trials with multiple endpoints ⋮ Sequential monitoring of response-adaptive randomized clinical trials with sample size re-estimation ⋮ Group-sequential response-adaptive designs for censored survival outcomes ⋮ Adaptive Multivariate Global Testing ⋮ Interim analysis of clinical trials based on urn models ⋮ Sequential precedence tests

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