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Closed Testing with Globaltest for Pathway Analysis

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Last update: 16 January 2024

Copyright license: GNU General Public License, version 3.0, GNU General Public License, version 2.0

Software version identifier: 2.0, 2.0.1

A shortcut procedure is proposed to implement closed testing for large-scale multiple testings, especially with the global test. This shortcut is asymptotically equivalent to closed testing and post hoc. Users could detect any possible sets of features or pathways with family-wise error rate controlled. The global test is powerful to detect associations between a group of features and an outcome of interest.




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