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Software:140053



CRANopenEBGMMaRDI QIDQ140053

EBGM Disproportionality Scores for Adverse Event Data Mining

John Ihrie, Travis Canida

Last update: 14 September 2023

Copyright license: GNU General Public License, version 3.0, GNU General Public License, version 2.0

Software version identifier: 0.8.3, 0.1.0, 0.2.0, 0.3.0, 0.4.0, 0.5.0, 0.6.0, 0.7.0, 0.8.0, 0.8.1, 0.8.2, 0.9.1

An implementation of DuMouchel's (1999) <doi:10.1080/00031305.1999.10474456> Bayesian data mining method for the market basket problem. Calculates Empirical Bayes Geometric Mean (EBGM) and posterior quantile scores using the Gamma-Poisson Shrinker (GPS) model to find unusually large cell counts in large, sparse contingency tables. Can be used to find unusually high reporting rates of adverse events associated with products. In general, can be used to mine any database where the co-occurrence of two variables or items is of interest. Also calculates relative and proportional reporting ratios. Builds on the work of the 'PhViD' package, from which much of the code is derived. Some of the added features include stratification to adjust for confounding variables and data squashing to improve computational efficiency. Includes an implementation of the EM algorithm for hyperparameter estimation loosely derived from the 'mederrRank' package.





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