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Facilities for Simulating from ODE-Based Models

Matthew L. Fidler, Melissa Hallow, Wenping Wang

Last update: 30 January 2024

Copyright license: GNU General Public License

Software version identifier: 2.0.12, 2.0.13, 2.0.6, 2.0.7, 2.0.8, 2.0.9, 2.0.10, 2.0.11, 2.0.14, 2.1.0, 2.1.1, 2.1.2

Facilities for running simulations from ordinary differential equation ('ODE') models, such as pharmacometrics and other compartmental models. A compilation manager translates the ODE model into C, compiles it, and dynamically loads the object code into R for improved computational efficiency. An event table object facilitates the specification of complex dosing regimens (optional) and sampling schedules. NB: The use of this package requires both C and Fortran compilers, for details on their use with R please see Section 6.3, Appendix A, and Appendix D in the "R Administration and Installation" manual. Also the code is mostly released under GPL. The 'VODE' and 'LSODA' are in the public domain. The information is available in the inst/COPYRIGHTS.




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