DelayedEffect.Design

CRANDelayedEffect.DesignMaRDI QIDQ86642

Sample Size and Power Calculations using the APPLE, SEPPLE, APPLE+ and SEPPLE+ Methods

Zhenzhen Xu

Last update: 21 August 2023

Copyright license: GNU General Public License, version 2.0

Software version identifier: 1.1.2, 0.0.4, 1.1.3

Description

Provides sample size and power calculations when the treatment time-lag effect is present and the lag duration is either homogeneous across the individual subject, or varies heterogeneously from individual to individual within a certain domain and following a specific pattern. The methods used are described in Xu, Z., Zhen, B., Park, Y., & Zhu, B. (2017) <doi:10.1002/sim.7157>.

Cites work

• Designing therapeutic cancer vaccine trials with delayed treatment effect

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