Optimization of the radiotherapy treatment plan
type: Item
instance of: scholarly article
title: Optimization of the radiotherapy treatment plan
zbMATH Open document ID: 0644.92003
DOI: 10.1016/0096-3003(88)90024-0
author: B. George
published in: Applied Mathematics and Computation
publication date: 1988-01-01T00:00:00Z
review text: A nonlinear minimization search method is proposed for optimizing the radiotherapy treatment plan. The basic implicit assumptions in clinical radiotherapeutic practice are reviewed in light of their implications for treatment-plan optimization. A tumor dose function is defined for unconstrained conditions pertaining to dose uniformity or minimized dose gradient over the tumor bed, and for constrained conditions relating to isodose curve levels or anatomic points of interest. The optimization strategy followed in the case of single and multiple beam variables is described and illustrated in a clinical case stuy.
Mathematics Subject Classification ID: 92C50
Mathematics Subject Classification ID: 90C90
zbMATH DE Number: 4051399
zbMATH Keywords: nonlinear minimization search method
zbMATH Keywords: radiotherapy treatment plan
zbMATH Keywords: treatment-plan optimization
zbMATH Keywords: tumor dose function
zbMATH Keywords: unconstrained conditions
zbMATH Keywords: isodose curve levels
zbMATH Keywords: clinical case stuy
MaRDI profile type: Publication
full work available at URL: 0096-3003(88)90024-0
OpenAlex ID: W1980944516
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description: scientific article; zbMATH DE number 4051399