A mathematical model of the P-glycoprotein pump as a mediator of multidrug resistance
type: Item
instance of: scholarly article
title: A mathematical model of the P-glycoprotein pump as a mediator of multidrug resistance
zbMATH Open document ID: 0752.92014
DOI: 10.1007/BF02460664
author: Seth Michelson
author: Doris Slate
published in: Bulletin of Mathematical Biology
publication date: 1993-01-16T00:00:00Z
Mathematics Subject Classification ID: 92C45
zbMATH DE Number: 94280
zbMATH Keywords: multidrug resistant phenotype
zbMATH Keywords: transmembrane protein
zbMATH Keywords: p170
zbMATH Keywords: P- glycoprotein
zbMATH Keywords: cytotoxic agents
zbMATH Keywords: cytoplasm
zbMATH Keywords: drug efflux pump
zbMATH Keywords: facilitated diffusion process
zbMATH Keywords: energy-dependent efflux of cytotoxic agents
zbMATH Keywords: ATP
zbMATH Keywords: Michaelis-Menten kinetics
zbMATH Keywords: partial differential equation
zbMATH Keywords: ordinary differential equation
zbMATH Keywords: dynamic algebraic calculation
zbMATH Keywords: stability analysis
zbMATH Keywords: ATP-ADP pool distribution
zbMATH Keywords: simulations
MaRDI profile type: Publication
Wikidata QID: Q52411309
cites work: A model for the resistance of tumor cells to cancer chemotherapeutic agents
cites work: The effect of cellular differentiation on the development of permanent drug resistance
cites work: A branching-process model for heterogeneous cell populations
cites work: On control of the function of the sodium-potassium pump in malignant cells
cites work: Periodic band pattern as a dissipative structure in ion transport systems with cylindrical shape
full work available at URL: https://doi.org/10.1007/bf02460664
OpenAlex ID: W4231114048
description: scientific article; zbMATH DE number 94280