Mathematical problems in modeling artificial heart
type: Item
instance of: scholarly article
title: Mathematical problems in modeling artificial heart
zbMATH Open document ID: 0920.93007
DOI: 10.1155/S1024123X95000159
published in: Mathematical Problems in Engineering
publication date: 1999-05-03T00:00:00Z
full work available at URL: https://eudml.org/doc/48224
review text: Summary: We discuss some problems arising in mathematical modeling of artificial hearts. The hydrodynamics of blood flow in an artificial heart chamber is governed by the Navier-Stokes equation, coupled with an equation of hyperbolic type subject to moving boundary conditions. The flow is induced by the motion of a diaphragm (membrane) inside the heart chamber attached to a part of the boundary and driven by a compressor (pusher plate). On one side of the diaphragm is the blood and on the other side is the compressor fluid. For a complete mathematical model it is necessary to write the equation of motion of the diaphragm and all the dynamic couplings that exist between its position, velocity and the blood flow in the heart chamber. This gives rise to a system of coupled nonlinear partial differential equations; the Navier-Stokes equation being of parabolic type and the equation for the membrane being of hyperbolic type. The system is completed by introducing all the necessary static and dynamic boundary conditions. The ultimate objective is to control the flow pattern so as to minimize hemolysis (damage to red blood cells) by optimal choice of geometry, and by optimal control of the membrane for a given geometry. The other clinical problems, such as compatibility of the material used in the construction of the heart chamber, and the membrane, are not considered in this paper. Also the dynamics of the valve is not considered here, though it is also an important element in the overall design of an artificial heart. We hope to model the valve dynamics later.
Mathematics Subject Classification ID: 93A30
Mathematics Subject Classification ID: 49K20
zbMATH DE Number: 1283580
zbMATH Keywords: coupled PDE
zbMATH Keywords: modeling of artificial hearts
zbMATH Keywords: Navier-Stokes equation
zbMATH Keywords: optimal control of the membrane
author: N. U. Ahmed
MaRDI profile type: Publication
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description: scientific article; zbMATH DE number 1283580