Exact analysis of a paired sibling data
type: Item
instance of: scholarly article
title: Exact analysis of a paired sibling data
zbMATH Open document ID: 1068.65021
DOI: 10.1007/BF02753910
published in: Computational Statistics
publication date: 2005-05-20T00:00:00Z
review text: The authors discuss the problem of statistical analysis of genetic study of sibling pair data of \textit{F. C. Fraser} and \textit{A. D. Hunter} [Etiologic relations among categories of congenital heart malformations. The American Journal of Cardiology 36, 793--796 (1975)]. The data is in the form of a triangular table with vanishing diagonal entries, so the problem of fitting parametric models to such tables is investigated using Monte-Carlo methods. Exact \(p\)-values are computed for a test of parameter significance and a test of goodness-of-fit which contradict the model of quasi-independence and confirm the previous analysis by \textit{B. MacGibbon} [A log-linear model of a paired sibling study. In Proceedings of Statistics'81 Canada Conference, Eds. Y. Chaubey, T. D. Dwivedi, 193-197 (1983)].
Mathematics Subject Classification ID: 62-08
Mathematics Subject Classification ID: 68P05
Mathematics Subject Classification ID: 62-07
Mathematics Subject Classification ID: 65D10
Mathematics Subject Classification ID: 65C05
zbMATH DE Number: 2169424
zbMATH Keywords: categorical data
zbMATH Keywords: genetic data
zbMATH Keywords: exact conditional test
zbMATH Keywords: exponential family
zbMATH Keywords: Monte-Carlo methods
zbMATH Keywords: quasi-independence
zbMATH Keywords: structural zeros
zbMATH Keywords: sibling pair data
zbMATH Keywords: fitting
author: I. H. Dinwoodie
author: Brenda Macgibbon
MaRDI profile type: Publication
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full work available at URL: https://doi.org/10.1007/bf02753910
OpenAlex ID: W2010986175
description: scientific article; zbMATH DE number 2169424