Computational cardiology. Modeling of anatomy, electrophysiology, and mechanics.
type: Item
instance of: scholarly article
title: Computational cardiology. Modeling of anatomy, electrophysiology, and mechanics.
zbMATH Open document ID: 1051.92025
author: Frank B. Sachse
published in: Lecture Notes in Computer Science
publication date: 2004-09-27T00:00:00Z
review text: The topic of this work is computer-based, mathematical modeling of the heart. The application of modeling as a research, development and clinical tool is stressed as a promising attempt to address many problems in cardiology, heart surgery and biomedical engineering. The modeling includes the areas of anatomy, electrophysiology, excitation propagation, force development and mechanics as well as the coupling of these areas. The work shows knowledge at molecular, cellular and macroscopic level, how these areas can be studied with measurements, and how these areas can be modeled with mathematical methods. Detailed information of phenomena on each of these levels is necessary to understand the ideas behind the modeling. Special attention is given to macroscopic and integrative modeling with the aim of reconstruction of the whole heart behavior. At macroscopic level anatomical models provide a basis for electrophysiological and mechanical models. Of particular interest is the assessment of influence of cardiac deformation to initiation and propagation of electrical excitation and to the force development. Various simulation studies are demonstrated, which provide information about this assessment. Detailed modeling of the macroscopic cardiac anatomy is commonly performed on base of medical imaging systems, which are used in clinical routine and research. The resulting data is transformed with methods of digital image processing to obtain a representation of anatomy, which is suitable for the target application. Different levels of spatial description can be distinguished, ranging from analytical, comprehensive approaches to detailed descriptions on base of millions of volume elements. Commonly, ultrasonic (US), magnetic resonance (MRT), and computed tomography (CT) are used for imaging of the heart. These imaging systems use tissue dependent variations of the acoustic impedance leading to reflection of ultrasonic waves and of their scattering, of the absorption of X-rays…
reviewed by: Fatima T. Adylova
Mathematics Subject Classification ID: 92C50
Mathematics Subject Classification ID: 92-08
Mathematics Subject Classification ID: 92C30
Mathematics Subject Classification ID: 92-02
Mathematics Subject Classification ID: 92C55
Mathematics Subject Classification ID: 65C20
Mathematics Subject Classification ID: 92C05
zbMATH DE Number: 2103826
zbMATH Keywords: computer models
zbMATH Keywords: cardiology
zbMATH Keywords: image processing
MaRDI profile type: Publication
Recommended article: Computational mechanics of the heart.
Recommended article: Q4350098
Recommended article: Computational electrocardiology: mathematical and numerical modeling
Recommended article: Computer modeling in cardiac electrophysiology. (Mini review)
Recommended article: Computational model of three-dimensional cardiac electromechanics
Recommended article: Multiphysics computational modeling in \(\mathcal{C}\mathbf{Heart}\)
Recommended article: Computational modeling of coupled cardiac electromechanics incorporating cardiac dysfunctions
Recommended article: Multiscale computational modelling of the heart
description: scientific article; zbMATH DE number 2103826