A schistosomiasis model with praziquantel resistance
type: Item
instance of: scholarly article
title: A schistosomiasis model with praziquantel resistance
zbMATH Open document ID: 1264.34163
DOI: 10.1155/2013/945767
author: Longxing Qi
author: Jing-An Cui
published in: Discrete Dynamics in Nature and Society
publication date: 2013-06-13T00:00:00Z
review text: Summary: A compartmental model is established for schistosomiasis with praziquantel resistance. The model considers the impact of genetic resistance and drug treatment on the transmission of schistosomiasis. We calculate the basic reproductive number and discuss the existence and stability of disease-free equilibrium, boundary equilibrium, and coexistence equilibrium. Our analysis shows that regardless of whether drug treatment leads to the emergence of resistance, once the impact of genetic resistance is larger, the resistant strain will be dominant, which is detrimental to the control of schistosomiasis. In addition, once the proportion of human with drug-resistant strain produced by drug treatment is larger, the number of human and snails with resistant strain is larger. This is not a good result for drug treatment with praziquantel.
Mathematics Subject Classification ID: 34K60
Mathematics Subject Classification ID: 92D30
Mathematics Subject Classification ID: 37N25
zbMATH DE Number: 6175142
Wikidata QID: Q58921280
MaRDI profile type: Publication
full work available at URL: https://doi.org/10.1155/2013/945767
OpenAlex ID: W1973116469
cites work: A schistosomiasis model with mating structure and time delay
cites work: The influence of drug treatment on the maintenance of schistosome genetic diversity
cites work: On the role of schistosome mating structure in the maintenance of drug resistant strains
cites work: Schistosomiasis models with density dependence and age of infection in snail dynamics
cites work: Schistosomiasis models with two migrating human groups
cites work: Q4255467
cites work: Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission
cites work: Computation of threshold conditions for epidemiological models and global stability of the disease-free equilibrium (DFE)
cites work: Influence of vertical and mechanical transmission on the dynamics of dengue disease
cites work: Stability of the endemic equilibrium in epidemic models with subpopulations
description: scientific article; zbMATH DE number 6175142