An analytical study of prostate-specific antigen dynamics
type: Item
instance of: scholarly article
title: An analytical study of prostate-specific antigen dynamics
zbMATH Open document ID: 1367.92054
DOI: 10.1155/2016/3929163
author: E. P. Esteban
author: Giovanni Deliz
author: Jaileen Rivera-Rodriguez
author: Stephanie M. Laureano
published in: Computational \& Mathematical Methods in Medicine
publication date: 2017-08-04T00:00:00Z
review text: Summary: The purpose of this research is to carry out a quantitative study of prostate-specific antigen dynamics for patients with prostatic diseases, such as benign prostatic hyperplasia (BPH) and localized prostate cancer (LPC). The proposed PSA mathematical model was implemented using clinical data of 218 Japanese patients with histological proven BPH and 147 Japanese patients with LPC (stages T2a and T2b). For prostatic diseases (BPH and LPC) a nonlinear equation was obtained and solved in a close form to predict PSA progression with patients' age. The general solution describes PSA dynamics for patients with both diseases LPC and BPH. Particular solutions allow studying PSA dynamics for patients with BPH or LPC. Analytical solutions have been obtained and solved in a close form to develop nomograms for a better understanding of PSA dynamics in patients with BPH and LPC. This study may be useful to improve the diagnostic and prognosis of prostatic diseases.
Mathematics Subject Classification ID: 92C50
zbMATH DE Number: 6756933
zbMATH Keywords: prostate-specific antigen dynamics
zbMATH Keywords: benign prostatic hyperplasia
zbMATH Keywords: localized prostate cancer
Wikidata QID: Q39106951
MaRDI profile type: Publication
full work available at URL: https://doi.org/10.1155/2016/3929163
OpenAlex ID: W2553795681
description: scientific article; zbMATH DE number 6756933