Formation of autapse connected to neuron and its biological function
type: Item
instance of: scholarly article
title: Formation of autapse connected to neuron and its biological function
zbMATH Open document ID: 1367.92025
DOI: 10.1155/2017/5436737
author: Shengli Guo
author: Ying Xu
author: Jun Ma
author: Jun Tang
author: Faris Alzahrani
author: Chun-Ni Wang
author: Aatef Hobiny
published in: Complexity
publication date: 2017-08-03T00:00:00Z
review text: Summary: Autapse is a specific synapse connected to the neuron via closed loop, and its functional adjusting is described by applying time-delayed feedback on the membrane potential of the neuron. This paper discussed the possible formation mechanism and biological function of autapse connection on neurons. We believe that the formation and growth of autapse connected to neuron can be associated with injury on axon and blocking in signal transmission; thus auxiliary loop is developed to form an autapse. When autapse is set up, it can propagate the signals and change the modes of electrical activities under self-adaption. Based on the cable neuron model, the injury on axon is generated by poisoning and blocking in ion channels (of sodium); thus the conductance of ion channels are changed to form injury-associated defects. Furthermore, auxiliary loop with time delay is designed to restore and enhance signal propagation by setting different time delays and feedback gains. The numerical studies confirmed that appropriate time delay and feedback gain in electric or chemical autapse can help signal (or wave generated by external forcing) propagation across the blocked area. As a result, formation of autapse could be dependent on the injury of neuron and further enhances the self-adaption to external stimuli.
Mathematics Subject Classification ID: 92C20
Mathematics Subject Classification ID: 92C05
zbMATH DE Number: 6755982
zbMATH Keywords: autapse
zbMATH Keywords: neuron
zbMATH Keywords: time-delayed feedback
zbMATH Keywords: formation mechanism
zbMATH Keywords: biological function
Wikidata QID: Q57878159
MaRDI profile type: Publication
full work available at URL: https://doi.org/10.1155/2017/5436737
OpenAlex ID: W2594589272
cites work: Modeling Single-Neuron Dynamics and Computations: A Balance of Detail and Abstraction
cites work: A phase plane analysis of neuron-astrocyte interactions
cites work: COLLECTIVE BEHAVIORS OF SPIRAL WAVES IN THE NETWORKS OF HODGKIN-HUXLEY NEURONS IN PRESENCE OF CHANNEL NOISE
cites work: TRANSITION OF ORDERED WAVES IN NEURONAL NETWORK INDUCED BY DIFFUSIVE POISONING OF ION CHANNELS
cites work: Emitting waves from defects in network with autapses
cites work: Collective temporal coherence for subthreshold signal encoding on a stochastic small-world Hodgkin-Huxley neuronal network
cites work: Autaptic pacemaker mediated propagation of weak rhythmic activity across small-world neuronal networks
cites work: Autaptic activity-induced synchronization transitions in Newman–Watts network of Hodgkin–Huxley neurons
cites work: Autapse-induced synchronization in a coupled neuronal network
cites work: AUTAPSE TURNS NEURON INTO OSCILLATOR
cites work: Collapse of ordered spatial pattern in neuronal network
description: scientific article; zbMATH DE number 6755982