An optimal control strategy for antiretroviral treatment of HIV infection in presence of immunotherapy
type: Item
instance of: scholarly article
title: An optimal control strategy for antiretroviral treatment of HIV infection in presence of immunotherapy
zbMATH Open document ID: 1494.37056
author: Bhagya Jyoti Nath
author: Hemanta Kumar Sarmah
author: Helmut Maurer
published in: Qualitative Theory of Dynamical Systems
publication date: 2022-03-15T00:00:00Z
review text: This paper proposes and presents a stability analysis of an HIV infection model incorporating the effects of antiretroviral drugs and immunotherapy. The authors study an optimal control problem to maximize healthy CD4+ T cells with minimum cost and side effects of drugs. By using discretization and large-scale optimization methods, they obtain optimal treatment strategies for antiretroviral drugs and immune boosting drugs.
reviewed by: Hongying Shu
Mathematics Subject Classification ID: 37N25
Mathematics Subject Classification ID: 37N35
Mathematics Subject Classification ID: 92B05
Mathematics Subject Classification ID: 49K15
Mathematics Subject Classification ID: 92D30
zbMATH DE Number: 7489695
zbMATH Keywords: optimal control
zbMATH Keywords: HIV infection
zbMATH Keywords: Pontryagin's maximum principle
zbMATH Keywords: immunotherapy
zbMATH Keywords: antiretroviral drugs
describes a project that uses: SOCS
describes a project that uses: Ipopt
describes a project that uses: AMPL
MaRDI profile type: Publication
full work available at URL: s12346-022-00564-3
OpenAlex ID: W4210395281
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DOI: 10.1007/S12346-022-00564-3
description: scientific article; zbMATH DE number 7489695