Levels of multiallelic overdominance fitness, heterozygote excess and heterozygote deficiency
type: Item
instance of: scholarly article
title: Levels of multiallelic overdominance fitness, heterozygote excess and heterozygote deficiency
zbMATH Open document ID: 0696.92015
DOI: 10.1016/0040-5809(90)90031-P
author: Samuel Karlin
published in: Theoretical Population Biology
publication date: 1990-01-01T00:00:00Z
review text: New concepts and results on selection models with multiple alleles are discussed. Most of the models considered by the author are one-locus systems, partially because the study of multi-locus systems effectively reduces to one-locus models when tight linkage and fitness interactions occur. The notion of heterozygote excess (or deficiency) is introduced for multi-allelic systems by referring to the eigenvalues of the corresponding genotype frequency matrix. Also the notion of heterozygote advantage is extended from its traditional meaning for two-allele viability models to the case of multiple alleles by defining four different levels of overdominance. These concepts are examined in the context of viability selection models and kin selection models.
Mathematics Subject Classification ID: 92D10
zbMATH DE Number: 4141863
zbMATH Keywords: selection models
zbMATH Keywords: multiple alleles
zbMATH Keywords: one-locus systems
zbMATH Keywords: tight linkage
zbMATH Keywords: fitness interactions
zbMATH Keywords: heterozygote excess
zbMATH Keywords: multi-allelic systems
zbMATH Keywords: eigenvalues
zbMATH Keywords: genotype frequency matrix
zbMATH Keywords: heterozygote advantage
zbMATH Keywords: levels of overdominance
zbMATH Keywords: viability selection models
zbMATH Keywords: kin selection models
reviewed by: G. Karigl
MaRDI profile type: Publication
Wikidata QID: Q46159132
cites work: Q5659379
cites work: Q3856478
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cites work: Q3289487
cites work: Population genetic theory of kin selection: Multiple alleles at one locus
full work available at URL: 0040-5809(90)90031-p
OpenAlex ID: W1994116727
description: scientific article; zbMATH DE number 4141863