A mechanistic systems pharmacology modeling platform to investigate the effect of PD-L1 expression heterogeneity and dynamics on the efficacy of PD-1 and PD-L1 blocking antibodies in cancer (Q2029579)
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scientific article; zbMATH DE number 7354808
| Language | Label | Description | Also known as |
|---|---|---|---|
| English | A mechanistic systems pharmacology modeling platform to investigate the effect of PD-L1 expression heterogeneity and dynamics on the efficacy of PD-1 and PD-L1 blocking antibodies in cancer |
scientific article; zbMATH DE number 7354808 |
Statements
A mechanistic systems pharmacology modeling platform to investigate the effect of PD-L1 expression heterogeneity and dynamics on the efficacy of PD-1 and PD-L1 blocking antibodies in cancer (English)
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3 June 2021
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checkpoint inhibitors
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cancer immunotherapy
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tumor heterogeneity
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receptor dynamics
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virtual patients
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PD-1
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PD-L1
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cytotoxic T cells
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non-tumor immune cells
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immunological synapse
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0.7768838405609131
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0.7561240196228027
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0.7384182810783386
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