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Identification of a pharmacokinetic two-compartment model application to the case of salicylates administered to rabbit - MaRDI portal

Identification of a pharmacokinetic two-compartment model application to the case of salicylates administered to rabbit (Q3748859)

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Identification of a pharmacokinetic two-compartment model application to the case of salicylates administered to rabbit
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    Identification of a pharmacokinetic two-compartment model application to the case of salicylates administered to rabbit (English)
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    1986
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    nonlinear programming method of conjugate-gradient type
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    drug kinetics
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    pharmacokinetic two-compartment open model
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    absorption
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    Aspirin
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    rabbits
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    lysine acetylsalicylate
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    sodium salicylate
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    transfer
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    elimination
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    rate constants
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    first-order kinetics
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    coupled linear differential equations
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    numerical tests
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    computer simulation study
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    finite difference discretization method
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    optimal therapeutic treatments
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