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Modelling how increased Cathepsin B/L and decreased TMPRSS2 usage for cell entry by the SARS-CoV-2 Omicron variant may affect the efficacy and synergy of TMPRSS2 and Cathepsin B/L inhibitors - MaRDI portal

Modelling how increased Cathepsin B/L and decreased TMPRSS2 usage for cell entry by the SARS-CoV-2 Omicron variant may affect the efficacy and synergy of TMPRSS2 and Cathepsin B/L inhibitors (Q6078351)

From MaRDI portal





scientific article; zbMATH DE number 7742802
Language Label Description Also known as
English
Modelling how increased Cathepsin B/L and decreased TMPRSS2 usage for cell entry by the SARS-CoV-2 Omicron variant may affect the efficacy and synergy of TMPRSS2 and Cathepsin B/L inhibitors
scientific article; zbMATH DE number 7742802

    Statements

    Modelling how increased Cathepsin B/L and decreased TMPRSS2 usage for cell entry by the SARS-CoV-2 Omicron variant may affect the efficacy and synergy of TMPRSS2 and Cathepsin B/L inhibitors (English)
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    27 September 2023
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    SARS-CoV-2
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    COVID-19
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    Omicron
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    spike protein
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    TMPRSS2
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    Cathepsin
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    mathematical modelling
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    viral kinetics
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    drug synergy
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