Incorporating patient-reported outcomes in dose-finding clinical trials

DOI10.1002/SIM.8402zbMATH Open1546.62442MaRDI QIDQ6627303

Xiaoqi Lu, Bin Cheng, Shing M. Lee

Publication date: 29 October 2024

Published in: Statistics in Medicine (Search for Journal in Brave)

zbMATH Keywords

maximum tolerated dosecontinual reassessment methodphase I trialrobust modelingmultiple toxicity constraints

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites Work

• Continual Reassessment Method: A Practical Design for Phase 1 Clinical Trials in Cancer
• On the consistency of the continual reassessment method with multiple toxicity constraints
• Continual reassessment method with multiple toxicity constraints
• Consistency of continual reassessment method under model misspecification

Related Items (1)

Application of the patient-reported outcomes continual reassessment method to a phase I study of radiotherapy in endometrial cancer

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