Deconstructing the contributions of heterogeneity to combination treatment of hormone-sensitive breast cancer

DOI10.1007/978-3-031-58516-6_5MaRDI QIDQ6651987

Jenna A. Moore-Ott, Adrianne L. Jenner, Samantha Linn, Morgan Craig, Wenjing Zhang, Robyn Shuttleworth

Publication date: 11 December 2024

zbMATH Keywords

ordinary differential equationsheterogeneitymathematical modelingCDK4/6 inhibitionfulvestranthormone-sensitive breast cancerpalbociclib

Mathematics Subject Classification ID

Medical applications (general) (92C50) Qualitative investigation and simulation of ordinary differential equation models (34C60)

Cites Work

• Mathematical modeling of ER-positive breast cancer treatment with AZD9496 and palbociclib
• Impact of estrogen population pharmacokinetics on a QSP model of mammary stem cell differentiation into myoepithelial cells

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