A two-stage group-sequential design for delayed treatment responses with the possibility of trial restart

DOI10.1002/SIM.10061zbMATH Open1546.62661MaRDI QIDQ6615879

Stephen Schüürhuis, F. Konietschke, Cornelia Ursula Kunz

Publication date: 8 October 2024

Published in: Statistics in Medicine (Search for Journal in Brave)

zbMATH Keywords

conditional powerdelayed responsegroup-sequential designerror-spendingpipeline data

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10)

Cites Work

• Title not available (Why is that?)
• Computation of multivariate normal and \(t\) probabilities
• Group Sequential and Confirmatory Adaptive Designs in Clinical Trials
• Incorporating Data Received after a Sequential Trial Has Stopped into the Final Analysis: Implementation and Comparison of Methods
• Pushing the Limits of Contemporary Statistics: Contributions in Honor of Jayanta K. Ghosh
• Adaptive Sample Size Calculations in Group Sequential Trials
• Design and analysis of group sequential tests based on the type I error spending rate function
• Group Sequential Tests for Delayed Responses (with discussion)
• Conditional power and friends: the why and how of (un)planned, unblinded sample size recalculations in confirmatory trials

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